The project brings together the University of Ljubljana, Faculty of Chemistry and Chemical Technology, the Jožef Stefan Institute, and JAFRAL, with the aim of developing two target products: nanobodies against the tau protein, which is associated with several neurodegenerative diseases, and a plasmid vector for gene therapy applications.
The project will explore the development and selection of highly specific nanobodies targeting pathogenic forms of tau, as well as a plasmid-based vector designed as a potential safer alternative to viral vectors for gene therapy. Particular attention will be given to the use of an antibiotic-resistance-free selection system, supporting improved biological safety.
Through its expertise in biotechnology development and manufacturing, JAFRAL contributes to the project with knowledge and capabilities relevant to the development and production of advanced biological products.
Read more about the project on the: Jafral pDNA&Nb: Konstrukti za proizvodnjo nanoteles in vektorjev za gensko zdravljenje: FKKT